Lyme Disease and Biotoxins: Managing Herxheimer Flares with Functional Medicine Lyme disease and tick borne diseases are complicated illnesses and because of that, treatment can be complex. Patients who've gone through treatment will often say your symptoms get worse before they get better. Lyme Disease Antioxidant: Support For Recovery Stop Herx Reactions 80% Success Managing Lyme Die Off Feeling worse before you feel better? It might be a Herx. Also called a Jarisch Herxheimer reaction, herxing happens when Lyme microbes are killed off and release toxins into your system, sparking a Hypercoagulation in Lyme Disease Dr. Todd Maderis