An integrative multi omics analysis leveraging Mendelian randomization and subsequent experimental validation prioritizes glutathione S transferase mu 5 (GSTM5) as a genomic stability related gene and a therapeutic vulnerability to PLK1 inhibition in Frontiers The Metabolic Mechanisms of Breast Cancer Metastasis Diet and Supplements in Cancer Prevention Association of glutathione S transferase T1, M1, and P1 polymorphisms TCRM Dove Medical Press International Journal of Oncology Frontiers Glutathione responsive and exhausting metal nanomedicines for robust synergistic cancer therapy