Initial clinical appearance with melanotic macules located on lower Download Scientific Diagram Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Pigmented Lesions Springer Nature Link Mucosal melanocytic macules Melanotic Macules, Naevi, and Melanoma Springer Nature Link