Data summary: IL 4 regulates glutathione levels in the liver and lung Download Scientific Diagram Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Tylenol and Glutathione: A Closer Look At Their Relationship Is Tylenol Safe During Pregnancy? Risk Factors, Not Causation Exposure to acetaminophen and all its metabolites upon 10, 15, and 20 mg kg intravenous acetaminophen in very preterm infants Pediatric Research Acetaminophen Depletes Glutathione Essential Formulas