Oral Melanotic Macule: Symptoms and Treatment Skinsight Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Oral melanotic macula on the upper gingival mucosa on a 40 year old Download Scientific Diagram Orale melanosis Melanotic macules of the tongue in a newborn Journal of the American Academy of Dermatology This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips.