Methylenetetrahydrofolate (MTHFR), the One Carbon Cycle, and Cardiovascular Risks Let's clear something up about MTHFR. You've probably heard it talked about online. Sometimes it's overhyped. Sometimes it's ignored. The truth is somewhere in the middle. MTHFR is a gene that affects Understanding MTHFR and Glutathione Detoxification MTHFR Gene Polymorphisms: A Single Gene with Wide Ranging Clinical ImplicationsA Review MTHFR 6 Support MakeWell Global An analysis of Methylenetetrahydrofolate reductase and Glutathione S transferase omega 1 genes as modifiers of the cerebral response to ischemia BMC Neurology Springer Nature Link